iReal Pro has several features to personalize and sharpen your practice.
Automatic transposition and tempo increase shift the key and raise the tempo at every repeat. Looping focuses your practice on a tricky section. Change a song's time signature in the editor to practice odd meters, hide the position marker for an extra challenge, and use the Mixer to remix or mute the band. iReal Pro also shows each backing track's exact length, so you can plan a precise practice session.
For the full guide with screenshots, see Advanced practice techniques on the iReal Pro website.